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アッセイ
99%
形状
solid
bp
234 °C (lit.)
mp
36-39 °C (lit.)
官能基
carboxylic acid
SMILES記法
CC1(CCCCC1)C(O)=O
InChI
1S/C8H14O2/c1-8(7(9)10)5-3-2-4-6-8/h2-6H2,1H3,(H,9,10)
InChI Key
REHQLKUNRPCYEW-UHFFFAOYSA-N
関連するカテゴリー
詳細
1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats.
アプリケーション
1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites.
生物化学的／生理学的作用
1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
213.8 °F - closed cup
引火点(℃)
101.00 °C - closed cup
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
142824-1G:
142824-10G:
142824-VAR:
142824-BULK:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
V P Poluianov
Sudebno-meditsinskaia ekspertiza, 35(1), 31-32 (1992-01-01)
Method of extraction-atomic absorption detection of arsenic in biologic material using naphthenic acid was developed and tested. Method can be used for arsenic detection in postmortem material. It differs from the known method by its accuracy, reliability and simple use.
Effects of 1-methyl cyclohexane carboxylic acid (CCA) on cellular energetics in neuroblastoma cells.
B Croizat et al.
Biochemical and biophysical research communications, 103(3), 1044-1051 (1981-12-15)
J C Larcher et al.
Experimental cell research, 203(1), 72-79 (1992-11-01)
Adriamycin, an anticancer agent acting on topoisomerase II, promotes the arrest of cell division and neurite extension in a "neurite-minus" murine neuroblastoma cell line, N1A-103. This morphological differentiation is accompanied by a blockade in the S phase of the cell
A J Sadeque et al.
The Journal of pharmacology and experimental therapeutics, 283(2), 698-703 (1997-11-14)
Cytochrome P450-dependent desaturation of the anticonvulsant drug valproic acid (VPA) results in formation of the hepatotoxin, 4-ene-VPA. Polytherapy with other anticonvulsants which are known P450 inducers increases the flux through this bioactivation pathway. The aim of the present study was
S A Fischkoff et al.
Journal of biological response modifiers, 3(2), 132-137 (1984-01-01)
The anticonvulsant drug 1-methyl-1-cyclohexanecarboxylic acid ( MCCA ) has been shown to cause maturation of murine neuroblastoma cells in vitro at concentrations that are pharmacologically achievable. HL-60 human promyelocytic leukemia cells cultured with this drug underwent a dose-dependent decrease in
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