700054P

5α,6β-dihydroxycholestanol

Avanti Research^™ - A Croda Brand

• 別名: 3β,5α,6β-trihydroxycholestane
• 実験式（ヒル表記法）: C₂₇H₄₈O₃
• CAS番号: 1253-84-5
• 分子量: 420.67
• MDL番号: MFCD00021171
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 詳細: Cholestane-3β,5α,6β-triol
• アッセイ: >99% (TLC)
• フォーム: powder
• 包装: pkg of 1 × 25 mg (700054P-25mg); pkg of 1 × 5 mg (700054P-5mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O[C@]21[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)C[C@H]2O)(CC[C@@H](C1)O)C
• InChI: 1S/C27H48O3/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24(29)27(30)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28-30H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27+/m1/s1
• InChI Key: YMMFNKXZULYSOQ-RUXQDQFYSA-N

詳細

詳細

5α,6β-dihydroxycholestanol is a structural derivative of cholesterol. It is produced by the low-density lipoprotein oxidation (LDL) and is a cholesterol autooxidation product. 5α,6β-dihydroxycholestanol is an abundant oxysterol.

アプリケーション

5α,6β-dihydroxycholestanol has been used as a cholesterol oxidation product in reversed phase chromatography (RP-HPLC) and mass spectroscopy analysis. It may be used as an internal standard in tandem mass spectrometry (MS/MS analysis) of plasma samples.

生物化学的／生理学的作用

5α,6β-dihydroxycholestanol (5α,6α-diOH-Chol) or cholestan-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It exhibits neuroprotective functionality during central nervous system (CNS) ischemia.

包装

5 mL Amber Glass Screw Cap Vial (700054P-25mg)

5 mL Amber Glass Screw Cap Vial (700054P-5mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable