06-1115

Anti-Interleukin-18 (IL-18) Antibody

from rabbit, purified by affinity chromatography

• 別名: interleukin 18 (interferon-gamma-inducing factor), IL-1 gamma, IFN-gamma-inducing factor, iboctadekin, interleukin-18, Interleukin-1 gamma, Iboctadekin, Interferon gamma-inducing factor
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• クローン: polyclonal
• application: IHC; WB
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• citations: 3

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• 化学種の反応性（ホモロジーによる予測）: rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBIアクセッション番号: NP_001553
• UniProtアクセッション番号: Q14116
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... IL18(3606)

詳細

詳細

IL-18 has been shown to be a pro-inflammatory cytokine that induces interferon-gamma. IL-18 has also been found to have the ability to activate nuclear factor-kappaB (NFkB), express Fas ligand, induce CC and CXC chemokines, and also has been found to increase the production of viable human immunodeficiency virus. IL-18 has been linked to syndromes displaying symptoms of chronic low-levels of inflammation. IL-18 also seems to have some control over homeostasis and behavior in the central nervous system as well as neuroinflammatory activity.

免疫原

KLH-conjugated linear peptide corresponding to human Interleukin-18.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
サイトカイン及びサイトカイン受容体

This Anti-Interleukin-18 (IL-18) Antibody is validated for use in WB, IH(P) for the detection of Interleukin-18 (IL-18).

Western Blot (Snap i.d.) Analysis: 5 µg/mL from a previous lot detected IL-18 in 10 µg of human tonsil tissue lysate.

Immunohistochemistry Analysis: A 1:600 dilution from a previous lot detected IL-18 in normal human spleen tissue.

品質

Evaluated by Western Blot in human tonsil tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected IL-18 in 10 µg of human tonsil tissue lysate.

ターゲットの説明

~22 kDa observed

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Human tonsil tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable