07-436-AF488

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate

0.5 mg/mL, from rabbit

• 別名: Histone H3.1t, H3/t, H3t, H3/g
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 488
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 化学種の反応性: human
• 化学種の反応性（ホモロジーによる予測）: vertebrates (based on 100% sequence homology)
• 濃度: 0.5 mg/mL
• テクニック: immunocytochemistry: suitable
• NCBIアクセッション番号: NM_003493
• UniProtアクセッション番号: Q16695
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: monomethylation (Lys4)
• 遺伝子情報: human ... H3C1(8350)

詳細

詳細

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.

免疫原

Linear peptide corresponding to Histone H3 monomethylated at Lys4.

アプリケーション

This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).

品質

Evaluated by Immunocytochemisty Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

ターゲットの説明

~17 kDa observed (Refer to Cat. No. 07-436)

物理的形状

Purified rabbit Alexa Fluor^™ 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.

法的情報

ALEXA FLUOR is a trademark of Life Technologies

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable