218755

Caspase-4 Inhibitor I

The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

• 別名: Caspase-4 Inhibitor I, Ac-LEVD-CHO
• 実験式（ヒル表記法）: C₂₂H₃₆N₄O₉
• CAS番号: 402832-01-3
• 分子量: 500.54
• MDL番号: MFCD08703162
• UNSPSCコード: 12352200
• NACRES: NA.54

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: lyophilized solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: water: 1 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: N([C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)CCC(=O)O
• InChI: 1S/C22H36N4O9/c1-11(2)8-16(23-13(5)28)21(34)25-15(6-7-17(29)30)20(33)26-19(12(3)4)22(35)24-14(10-27)9-18(31)32/h10-12,14-16,19H,6-9H2,1-5H3,(H,23,28)(H,24,35)(H,25,34)(H,26,33)(H,29,30)(H,31,32)/t14-,15-,16-,19-/m0/s1

詳細

詳細

A reversible caspase-4 (ICH-2) inhibitor.

A reversible caspase-4 inhibitor.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
caspase-4

Product does not compete with ATP.

Reversible: yes

警告

Toxicity: Standard Handling (A)

シーケンス

Ac-Leu-Glu-Val-Asp-CHO

再構成

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable