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Merck
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主要文書

安全性情報

AB15552

Sigma-Aldrich

Anti-AT1 Receptor Antibody

Chemicon®, from rabbit

別名:

Angiotensin II receptory type 1, AGTR1

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41
クローン:
polyclonal
application:
FACS
ICC
IHC
WB
化学種の反応性:
mouse, rat, human
テクニック:
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
citations:
14

由来生物

rabbit

品質水準

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

化学種の反応性

mouse, rat, human

メーカー/製品名

Chemicon®

テクニック

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... AGTR1(185)

特異性

Recognizes AT1 Receptor (Angiotensin II receptory type 1, AGTR1).
The immunogen sequence is identical in canine.

免疫原

Purified peptide from the N-terminus of human AT1 Receptor (Accession number P30556).

アプリケーション

Research Category
ニューロサイエンス
Research Sub Category
CNSによる代謝制御

ホルモン及び受容体
Anti-AT1 Receptor Antibody detects level of AT1 Receptor & has been published & validated for use in FC, IC, IH & WB.
Western blot: 1:200-1:500 using ECL on rat liver, rat kidney, mouse heart and mouse kidney lysate.
Immunohistochemistry on rat brain sections.
Immunocytochemistry: 1:100
Flow cytometry, indirect: 5-10 µg of antibody /1 x 106 cells
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.

物理的形状

ImmunoAffinity Purified
Format: Purified
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

保管および安定性

Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

アナリシスノート

Control
Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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危険有害性情報

注意書き

危険有害性の分類

Aquatic Chronic 3

保管分類コード

11 - Combustible Solids

WGK

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

毒物及び劇物取締法

毒物

Jan Code

AB15552-200UL:
AB15552-50UL:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Francielle Graus-Nunes et al.
World journal of hepatology, 11(4), 359-369 (2019-05-23)
Obesity has been associated with hepatic overexpression of the renin-angiotensin system (RAS). To evaluate the action of two angiotensin II (ANGII) receptor blockers (losartan or telmisartan) on the modulation of local hepatic RAS and the resulting metabolic effects in a
Julius Benicky et al.
Cellular and molecular neurobiology, 32(8), 1353-1365 (2012-07-31)
Commercially available Angiotensin II AT1 receptor antibodies are widely employed for receptor localization and quantification, but they have not been adequately validated. In this study, six commercially available AT1 receptor antibodies were characterized by established criteria: sc-1173 and sc-579 from
null
Mehmet Hakan Ozdener et al.
Nutrients, 14(13) (2022-07-10)
In addition to the α, β, and γ subunits of ENaC, human salt-sensing taste receptor cells (TRCs) also express the δ-subunit. At present, it is not clear if the expression and function of the ENaC δ-subunit in human salt-sensing TRCs
Chien-Ning Hsu et al.
Nutrients, 11(12) (2019-12-08)
Hypertension can originate in early life caused by perinatal high-fat (HF) consumption. Gut microbiota and their metabolites short chain fatty acids (SCFAs), trimethylamine (TMA), and trimethylamine N-oxide (TMAO) are involved in the development of hypertension. Despite the beneficial effects of

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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