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由来生物
rabbit
品質水準
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
化学種の反応性
mouse, human
メーカー／製品名
Chemicon®
テクニック
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TNC(3371)
詳細
Tenascin is known to play an active role in development of central nervous system and mesenchymal-derived organs, exist in the vasculature of tumors in adults, and function in cell adhesion.
特異性
Reactivity with other species has not been confirmed, but likely to react with all mammalian species.
Reacts strongly with tenascin from human and mouse in both Western blotting and immunohistochemistry. While it has not been tested, it should also react strongly in these applications with tenascin from all mammalian species.
免疫原
Purified human tenascin from glioma culture supernatant.
アプリケーション
Research Category
細胞骨格
細胞骨格
Research Sub Category
ECMタンパク質
ECMタンパク質
This Anti-Tenascin Antibody is validated for use in WB, IH(P) for the detection of Tenascin.
Western blot: 0.5 - 1.0 μg/mL; recognizes 250-350 kDa polypeptides in reduced samples.
Immunohistochemistry: 10 to 20 μg/mL in paraffin embedded tissues
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 10 to 20 μg/mL in paraffin embedded tissues
Optimal working dilutions must be determined by end user.
物理的形状
Affinity purified using immobilized human tenascin; presented as a liquid in PBS containing no preservatives.
保管および安定性
Maintain at -20°C for up to 12 months from date of receipt. Aliquot to avoid repeated freeze/thaw cycles.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB19011:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Mariska T Meijer et al.
Frontiers in immunology, 12, 600979-600979 (2021-03-30)
Tenascin C (TNC) is an extracellular matrix glycoprotein that recently emerged as an immunomodulator. TNC-deficient (TNC-/-) mice were reported to have a reduced inflammatory response upon systemic administration of lipopolysaccharide, the toxic component of gram-negative bacteria. Here, we investigated the
Loss of caveolin-1 from bronchial epithelial cells and monocytes in human subjects with asthma.
Bains, SN; Tourkina, E; Atkinson, C; Joseph, K; Tholanikunnel, B; Chu, HW; Riemer et al.
Allergy null
Fernando García-Marqués et al.
Molecular & cellular proteomics : MCP, 15(5), 1740-1760 (2016-02-20)
The coordinated behavior of proteins is central to systems biology. However, the underlying mechanisms are poorly known and methods to analyze coordination by conventional quantitative proteomics are still lacking. We present the Systems Biology Triangle (SBT), a new algorithm that
Subhayan Sur et al.
International journal of molecular sciences, 22(6) (2021-04-04)
SARS-CoV-2 infection can cause cytokine storm and may overshoot immunity in humans; however, it remains to be determined whether virus-induced soluble mediators from infected cells are carried by exosomes as vehicles to distant organs and cause tissue damage in COVID-19
Minsuk Choi et al.
Cancer research, 78(24), 6890-6902 (2018-10-26)
: Although cancer stem cells (CSC) are thought to be responsible for tumor recurrence and resistance to chemotherapy, CSC-related research and drug development have been hampered by the limited supply of diverse, patient-derived CSC. Here, we present a functional polymer
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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