コンテンツへスキップ
Merck
すべての画像(1)

主要文書

安全性情報

MAB201

Sigma-Aldrich

Mouse Anti-Rabbit light chain Antibody

Chemicon®, from mouse

ログイン組織・契約価格を表示する


About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.46

由来生物

mouse

品質水準

結合体

unconjugated

抗体製品の状態

ascites fluid

クローン

monoclonal

化学種の反応性

rabbit

メーカー/製品名

Chemicon®

テクニック

ELISA: suitable
western blot: suitable

アイソタイプ

IgG1κ

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

詳細

Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and gamma light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.

特異性

Minimal cross-reaction with bovine, goat, Armenian hamster, horse, human, mouse, rat, and sheep.
The antibody reacts strongly with native primary antibodies primarily with kappa light chains. It is not suitable for detecting lambda light chains. The antibody does not react with the heavy chain of rabbit IgG. The antibody has been tested by ELISA and adsorbed to ensure minimal cross-reaction with bovine, goat, Armenian hamster, horse, human, mouse, rat, and sheep immunoglobulins.

免疫原

Epitope: Kappa light chain
Prepared from rabbit IgG light chain.

アプリケーション

Research Category
二次抗体及びコントロール抗体
Research Sub Category
フラグメント特異的二次抗体
This Mouse anti-Rabbit light chain Antibody is validated for use in ELISA, WB for the detection of Rabbit light chain.

ターゲットの説明

25 kDa

物理的形状

Ascites
Isolated from ascites by chromatographic procedures. Liquid in 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6.

保管および安定性

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MAB201:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Charles E Evans et al.
Neurobiology of aging, 75, 136-149 (2018-12-21)
β-Amyloid (Aβ) accumulation is an early event of Alzheimer's disease (AD) pathogenesis. Inhibition of Aβ production by β-secretase (BACE) has been proposed as a potential therapeutic strategy for AD. However, BACE inhibitors lack specificity and have had limited clinical benefit.
Javier Garzón-Niño et al.
International journal of molecular sciences, 24(1) (2023-01-09)
The opioid peptide β-endorphin coexists in the pituitary and brain in its αN-acetylated form, which does not bind to opioid receptors. We now report that these neuropeptides exhibited opposite effects in in vivo paradigms, in which ligands of the sigma
Jon R Ward et al.
The Journal of biological chemistry, 285(30), 23147-23158 (2010-05-25)
The processing and regulated secretion of IL-1beta are critical points of control of the biological activity of this important pro-inflammatory cytokine. IL-1beta is produced by both monocytes and macrophages, but the rate and mechanism of release differ according to the
Michael J Tuvim et al.
The Journal of biological chemistry, 284(15), 9781-9787 (2009-02-12)
Synaptotagmin 2 (Syt2) functions as a low affinity, fast exocytic Ca(2+) sensor in neurons, where it is activated by Ca(2+) influx through voltage-gated channels. Targeted insertion of lacZ into the mouse syt2 locus reveals expression in mucin-secreting goblet cells of
Jung-Lin Wu et al.
Nature communications, 7, 12526-12526 (2016-08-25)
Crosslinking of B-cell receptor (BCR) sets off an apoptosis programme, but the underlying pathways remain obscure. Here we decipher the molecular mechanisms bridging B-cell activation and apoptosis mediated by post-translational modification (PTM). We find that O-GlcNAcase inhibition enhances B-cell activation

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)