PHR1341

サッカリン

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: サッカリン, 2,3-ジヒドロキシ-1,2-ベンゾイソチアゾール-3-オン-1,1-ジオキシド, 2-スルホ安息香酸イミド, o-安息香酸スルフィミド
• 実験式（ヒル表記法）: C₇H₅NO₃S
• CAS番号: 81-07-2
• 分子量: 183.18
• Beilstein: 6888
• EC Number: 201-321-0
• MDL番号: MFCD00005866
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823326
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. S0040000; traceable to USP 1607007
• APIファミリー: saccharin
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 226-229 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: O=C1NS(=O)(=O)c2ccccc12
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• InChI Key: CVHZOJJKTDOEJC-UHFFFAOYSA-N

詳細

詳細

Saccharin is a well-known non-carbohydrate, sulfonyl amide artificial sweetener and is generally used in the form of its calcium or sodium salt. It possesses a sweetening power of about 550 times more than that of saccharose. On losing the acidic imino hydrogen, it forms the corresponding nitro anion, which exhibits interesting coordination chemistry. It offers a bitter and metallic aftertaste which limits its use as an artificial sweetening agent.

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

アプリケーション

Saccharin can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

哺乳類の甘味物質です。ショウジョウバエにおいて、グルコース特異的なグリセロール味覚受容体結合部位の存在が提唱されています。

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC3561 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable