A5080

Amyloid β-Protein Fragment 22-35

≥95% (HPLC)

• 実験式（ヒル表記法）: C₅₉H₁₀₂N₁₆O₂₁S
• CAS番号: 144189-71-9
• 分子量: 1403.60
• MDL番号: MFCD00236784
• UNSPSCコード: 12352202
• PubChem Substance ID: 24890940
• NACRES: NA.32

特性

• 品質水準: 200
• アッセイ: ≥95% (HPLC)
• フォーム: powder
• UniProtアクセッション番号: P05067
• 保管温度: −20°C
• SMILES記法: CCC(C)C(NC(=O)C(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)CNC(=O)C(NC(=O)C(CC(O)=O)NC(=O)C(N)CCC(O)=O)C(C)C)C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(O)=O
• InChI: 1S/C59H102N16O21S/c1-11-30(7)47(57(93)65-25-42(79)67-36(21-28(3)4)52(88)70-35(59(95)96)18-20-97-10)75-58(94)48(31(8)12-2)74-49(85)32(9)66-41(78)24-63-51(87)34(15-13-14-19-60)69-53(89)37(22-40(62)77)72-55(91)39(27-76)68-43(80)26-64-56(92)46(29(5)6)73-54(90)38(23-45(83)84)71-50(86)33(61)16-17-44(81)82/h28-39,46-48,76H,11-27,60-61H2,1-10H3,(H2,62,77)(H,63,87)(H,64,92)(H,65,93)(H,66,78)(H,67,79)(H,68,80)(H,69,89)(H,70,88)(H,71,86)(H,72,91)(H,73,90)(H,74,85)(H,75,94)(H,81,82)(H,83,84)(H,95,96)
• InChI Key: KUDAPIFTNDCCFG-UHFFFAOYSA-N
• 遺伝子情報: human ... APP(351)

詳細

Amino Acid Sequence

Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met

生物化学的／生理学的作用

Has cytotoxic effect on cultured neurons from rat hippocampus in serum free medium. Also forms aggregates and fibrils similar to those of β-amyloid protein in senile plaque cores.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)