A6354

Anti-Adiponectin antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: Adiponectin Antibody, Anti-Adiponectin antibody produced in rabbit, Anti-Adipocyte Complement-Related Protein of 30 kDa
• MDL番号: MFCD03454695
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: WB CL
• クローン: polyclonal
• 化学種の反応性: mouse, human
• citations: 30
• テクニック: western blot (chemiluminescent): 0.5-1 μg/mL using using human plasma or placenta, or an extract of differentiated 3T3-L1 mouse cells.

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: mouse, human
• 濃度: ~1 mg/mL
• テクニック: western blot (chemiluminescent): 0.5-1 μg/mL using using human plasma or placenta, or an extract of differentiated 3T3-L1 mouse cells.
• UniProtアクセッション番号: Q15848
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ADIPOQ(9370) ; mouse ... Adipoq(11450)

詳細

詳細

Adiponectin is secreted from adipose tissue for the regulation of glucose and fatty acid break down.

Anti-Adiponectin is produced in rabbit using a synthetic peptide corresponding to amino acid residues of human adiponectin. Adiponectin, also designated as adipocyte complement-related protein of 30 kDa (Acrp30), AdipoQ, apM1, Gelatin-binding protein 28 kDa (GBP28) is an adipocyte-specific protein that circulates in the blood stream, where it accounts for approximately 0.01% of all plasma proteins. Adiponectin belongs to the complement factor C1q family that belongs to the soluble defense collagen superfamily. Adiponectin (ADIPOQ) protein has a carboxyl-terminal globular domain and an amino-terminal collagen domain.

It is recommended to dilute the antibody in phosphate buffered saline containing 0.5% non-fat dry milk for background staining reduction.

特異性

Rabbit Anti-Adiponectin antibody recognizes human and mouse adiponectin.

免疫原

ヒトアディポネクチンのアミノ酸残基225-244に相当する合成ペプチド(N末端システイン付加)のKLH結合体。

アプリケーション

Anti-Adiponectin antibody produced in rabbit has been used in western blotting and immunohistochemistry.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Rabbit Anti-Adiponectin antibody has been used for immunohistochemical and western blot applications.

生物化学的／生理学的作用

Adipose tissue has important roles in energy storage, glucose homeostasis and fat metabolism.(10) Increased adiponectin levels are associated with type I diabetes mellitus, anorexia nervosa, weight reduction, and chronic renal failure. Adiponectin (ADIPOQ) affects lipid catabolism by increasing fatty acid oxidation in muscle, modulates glucose uptake, alters liver gluconeogenesis and enhances insulin-sensitivity in both muscle and liver. ADIPOQ has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.

物理的形状

0.01 M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable