AV47141
Anti-ZDHHC17 (AB1) antibody produced in rabbit
affinity isolated antibody
別名:
抗HIP3抗体, 抗HYPH抗体, 抗KIAA0946抗体
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すべての画像(3)
About This Item
UNSPSCコード:
12352203
NACRES:
NA.41
結合体:
unconjugated
application:
IHC
WB
WB
クローン:
polyclonal
化学種の反応性:
rat, human, mouse, bovine, guinea pig, horse, rabbit, dog
citations:
4
テクニック:
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
73 kDa
化学種の反応性
rat, human, mouse, bovine, guinea pig, horse, rabbit, dog
濃度
0.5 mg - 1 mg/mL
テクニック
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ZDHHC17(23390)
関連するカテゴリー
免疫原
Synthetic peptide directed towards the middle region of human ZDHHC17
アプリケーション
Anti-ZDHHC17 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.
生物化学的／生理学的作用
ZDHHC17 is a palmitoyl acyl transferase (PAT) expressed primarily in insulin-positive cells in islets of Langerhans. Overexpression of HIP14 is related to a reduction in IL-1beta-induced NF-kappaB activity and it can also protect against IL-1beta-mediated apoptosis. Additionally, it is a ClipR-59 palmitoyltransferase that modifies the ClipR-59 plasma membrane binding and hence regulates the Akt signaling as well as Glut4 membrane translocation in adipocytes. It also facilitates the Mg2+ transport.
シーケンス
Synthetic peptide located within the following region: LFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKP
物理的形状
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AV47141-100UL:
AV47141-50UG:
最新バージョンのいずれかを選択してください：
Angela Goytain et al.
The Journal of biological chemistry, 283(48), 33365-33374 (2008-09-17)
Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. HIP14 protein has been shown to interact with huntingtin. HIP14 and a HIP14-like protein, HIP14L, with a 69% similarity reside in the Golgi and possess palmitoyl acyltransferase activity
Lukas Adrian Berchtold et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(37), E681-E688 (2011-06-28)
Type 1 diabetes (T1D) is a complex disease characterized by the loss of insulin-secreting β-cells. Although the disease has a strong genetic component, and several loci are known to increase T1D susceptibility risk, only few causal genes have currently been
Wenying Ren et al.
Molecular and cellular biology, 33(21), 4255-4265 (2013-09-05)
ClipR-59 interacts with Akt and regulates Akt compartmentalization and Glut4 membrane trafficking in a plasma membrane association-dependent manner. The association of ClipR-59 with plasma membrane is mediated by ClipR-59 palmitoylation at Cys534 and Cys535. To understand the regulation of ClipR-59
Activity-dependent post-translational regulation of palmitoylating and depalmitoylating enzymes in the hippocampus.
Abazari, et al.
Journal of Cell Science, 136 (2023)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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