おすすめの製品
品質水準
アッセイ
≥98% (HPLC)
フォーム
powder
保管条件
desiccated
色
white to off-white
溶解性
DMSO: ≥20 mg/mL
保管温度
2-8°C
SMILES記法
Cl.Clc1cncc(n1)N2CCNCC2
InChI
1S/C8H11ClN4.ClH/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13;/h5-6,10H,1-4H2;1H
InChI Key
PFIZGLUIYAZQFU-UHFFFAOYSA-N
生物化学的／生理学的作用
5-HT2Cセロトニン受容体の選択的アゴニストです。
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 3 Oral
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
M3199-5MG:
M3199-VAR:
M3199-25MG:
M3199-BULK:
最新バージョンのいずれかを選択してください：
Janet L Neisewander et al.
Behavioural pharmacology, 18(8), 791-800 (2007-11-09)
The extinction/reinstatement model has been used in this study to examine the role of 5-HT2C receptors in cocaine-seeking behavior elicited by cocaine-associated cues and cocaine-priming injections. Rats that had been trained to press a lever for cocaine (0.75 mg/kg/0.1 ml
Nathan S Pentkowski et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(10), 2037-2048 (2010-06-04)
Serotonin 2C receptor (5-HT(2C)R) agonists administered systemically attenuate both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking behavior. To further elucidate the function of these receptors in addiction-like processes, this study examined the effects of microinfusing the 5-HT(2C)R agonist MK212 (0
Ellen A Walker et al.
Neuropharmacology, 49(8), 1210-1219 (2005-09-17)
Serotonin(2C) (5-HT(2C)) receptors have been implicated to treat mood disorders such as depression and anxiety. In the present study, the capacities of two 5-HT(2C) agonists, MK212 and mCPP, to produce conditioned taste aversions in mice were evaluated. On two training
K S Gomes et al.
Progress in neuro-psychopharmacology & biological psychiatry, 33(7), 1261-1269 (2009-07-25)
A single exposure to the elevated plus-maze test (EPM) increases open arms avoidance and reduces or abolishes the anxiolytic-like effect of benzodiazepines assessed during a second trial, a phenomenon defined as "one-trial tolerance" (OTT). It has been emphasized that the
Antonio Pedro de Mello Cruz et al.
Psychopharmacology, 182(3), 345-354 (2005-09-01)
Although 5-HT2 receptors seem to play an important role in anxiety, results from numerous studies are still highly variable. Moreover, little is known about the behavioral effects of centrally administered 5-HT2 compounds in animal models of anxiety. The current study
資料
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