P4997
Anti-Potassium Channel KCa3.1 (Intermediate-conductance Ca2+-activated Potassium Channel 4) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
別名:
Anti-IKCa1, Anti-KCNN4, Anti-SK4
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すべての画像(3)
About This Item
結合体:
unconjugated
application:
WB
クローン:
polyclonal
化学種の反応性:
human, rat, mouse (predicted)
citations:
7
テクニック:
western blot: 1:200
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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
lyophilized powder
化学種の反応性
human, rat, mouse (predicted)
テクニック
western blot: 1:200
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KCNN4(3783)
mouse ... Kcnn4(16534)
rat ... Kcnn4(65206)
免疫原
synthetic peptide corresponding to amino acid residues 350-363 of rat KCa3.1. The sequence has 100% homology with human, mouse, and pig.
アプリケーション
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Immunofluorescence (1 paper)
Western Blotting (1 paper)
物理的形状
Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
Valentina Back et al.
Journal of thrombosis and haemostasis : JTH, 20(11), 2587-2600 (2022-07-23)
Within the vasculature platelets and endothelial cells play crucial roles in hemostasis and thrombosis. Platelets, like endothelial cells, possess intermediate conductance Ca2+ -activated K+ (IKCa ) channels and generate nitric oxide (NO). Although NO limits platelet aggregation, the role of
Yi-Je Chen et al.
PloS one, 8(11), e81006-e81006 (2013-12-07)
Allograft vasculopathy (AV) remains one of the major challenges to the long-term functioning of solid organ transplants. Although its exact pathogenesis remains unclear, AV is characterized by both fibromuscular proliferation and infiltration of CD4(+) memory T cells. We here tested
Eva M Grössinger et al.
Journal of immunology (Baltimore, Md. : 1950), 200(2), 749-757 (2017-12-17)
In inflammatory arthritis, the dysregulation of osteoclast activity by proinflammatory cytokines, including TNF, interferes with bone remodeling during inflammation through Ca2+-dependent mechanisms causing pathological bone loss. Ca2+-dependent CREB/c-fos activation via Ca2+-calmodulin kinase IV (CaMKIV) induces transcriptional regulation of osteoclast-specific genes
Lee-Way Jin et al.
Annals of clinical and translational neurology, 6(4), 723-738 (2019-04-26)
Microglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing neuroinflammation. To determine if KCa3.1
Katy M Roach et al.
PloS one, 8(12), e85244-e85244 (2014-01-07)
Idiopathic pulmonary fibrosis (IPF) is a common, progressive and invariably lethal interstitial lung disease with no effective therapy. We hypothesised that K(Ca)3.1 K(+) channel-dependent cell processes contribute to IPF pathophysiology. K(Ca)3.1 expression in primary human lung myofibroblasts was examined using
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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