S2071

Anti-Sodium Channel Na_V1.8 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• 別名: Anti-PN3, Anti-SCN10A
• MDL番号: MFCD08705520
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: rat
• テクニック: immunohistochemistry (frozen sections): suitable using adult rat DRG; western blot: 1:200 using rat DRG lysates
• UniProtアクセッション番号: Q62968
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SCN10A(6336) ; mouse ... Scn10a(20264) ; rat ... Scn10a(29571)

詳細

詳細

Sodium voltage-gated channel α subunit 10 (SCN10A) codes for Nav1.8 sodium channels. It is expressed in nociceptive neurons. This gene is mapped to human chromosome 3p22.2.

免疫原

peptide (C)EDEVAAKEGNSPGPQ corresponding to residues 1943-1957 of rat Na_v1.8. This sequence has 14/15 residues identical in mouse and 7/15 residues identical in human.

アプリケーション

Anti-Sodium Channel NaV1.8 antibody has been used in immunohistochemistry and immunocytochemistry.

生物化学的／生理学的作用

Sodium voltage-gated channel α subunit 10 (SCN10A) plays a major role in human pain. It is involved in the pathophysiology of cerebellar deficits in MS (multiple sclerosis).

ターゲットの説明

Anti-Sodium Channel Na_V1.8 specifically recognizes Na_V1.8. Voltage-gated sodium channels (VGSCs) are present in most excitable cells. They play a crucial role in regulating the cell excitability, being primarily responsible for the

物理的形状

Lyophilized from phosphate buffered saline, pH 7.4, with 1% bovine serum albumin, and 0.05 % sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable