SAB2900692

Anti-NTSR1 antibody produced in rabbit

affinity isolated antibody

• 別名: NT-1r, NT1 receptor, NTR, NTS1, NTSR1, Neurotensin receptor type 1
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: IHC
• クローン: polyclonal
• 化学種の反応性: human
• citations: 3
• テクニック: immunohistochemistry: 6 μg/mL

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: human
• テクニック: immunohistochemistry: 6 μg/mL
• UniProtアクセッション番号: P30989
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NTSR1(4923)

詳細

詳細

The neurotensin receptor 1 (NTSR1) gene has 4 exons and 3 introns and is 53.93 Kb long. NTSR1 is a member of the G protein-coupled receptor (GPCR) family. It consists of 4 extracellular and intracellular loops. It is expressed in the amygdal nucleus, ventral tegmental area, substantia nigra, striatum and entorhinal, and prefrontal cortices of the central nervous system.

免疫原

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human NTSR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Elephant (94%); Marmoset (89%); Hamster (83%).

アプリケーション

Anti-NTSR1 antibody produced in rabbit has been used in immunohistochemistry (IHC) (1:500).

生物化学的／生理学的作用

The neurotensin receptor 1 (NTSR1) plays a regulatory role in the initiation, proliferation, apoptosis, metastasis, and differentiation of tumors through several pathways. Overexpression of NTSR1 is seen in lung cancer, malignant prostatic tumors, and malignant cell lines. NTSR1 is a risk factor that participates in the progression of ductal breast cancer.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

1 mg/mLで供給

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable