SAB3500438

Anti-CLDN1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-CLD1, Anti-CLDN1, Anti-Claudin 1, Anti-ILVASC, Anti-SEMP1
• MDL番号: MFCD02096101
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA (i); ICC; IF; WB
• クローン: polyclonal
• 化学種の反応性: rat, mouse, human
• citations: 5
• テクニック: immunocytochemistry: suitable; immunofluorescence: suitable; indirect ELISA: suitable; western blot: suitable

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: rat, mouse, human
• テクニック: immunocytochemistry: suitable; immunofluorescence: suitable; indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: CAG33419
• UniProtアクセッション番号: O95832
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CLDN1(9076)

詳細

詳細

Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28.

免疫原

CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1.

生物化学的／生理学的作用

Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis.

特徴および利点

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関連事項

The action of this antibody can be blocked using blocking peptide SBP3500438.

物理的形状

PBS（0.02％ アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable