SAB4200230

Anti-DPP4/CD26 antibody, Mouse monoclonal

clone A6H, purified from hybridoma cell culture

• 別名: Monoclonal Anti-ADABP, Monoclonal Anti-ADCP2, Monoclonal Anti-DPPIV, Monoclonal Anti-TP103, Monoclonal Anti-dipeptidyl-peptidase 4
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: A6H, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human
• 濃度: ~4.0 mg/mL
• テクニック: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; indirect immunofluorescence: 20-40 μg/mL using methanol/acetone fixed HT-29 cells
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... DPP4(1803)

詳細

詳細

Monoclonal Anti-DPP4/CD26 (mouse IgG1 isotype) is derived from the hybridoma A6H produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human fetal homogenates. Dipeptidyl peptidase-4 (DPP4) belongs to the S9B protein family, which cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides and peptide hormones. It is a type II transmembrane glycoprotein, expressed on the surface of many cell types.

免疫原

human fetal homogenates.

アプリケーション

Monoclonal Anti-DPP4/CD26 antibody produced in mouse has been used in:

• enzyme linked immuno sorbent assay (ELISA)
• immunocytochemistry
• immunohistochemistry
• flow cytometry

生物化学的／生理学的作用

Dipeptidyl peptidase-4 (DPP4) is involved in the regulation of the biological activity of hormones and chemokines, such as glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. DPP4 inhibition maybe used to treat type 2 diabetes mellitus. It acts as a T cell activation molecule and regulates immunity and immune-mediated disorders.

物理的形状

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable