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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen ~55-70 kDa
交差性
mouse, rat, human
濃度
~1.0 mg/mL
テクニック
western blot: 0.5-1.0 μg/mL using rat spinal cord extracts (S1 fraction)
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SLC2A1(6513)
mouse ... Slc2a1(20525)
rat ... Slc2a1(24778)
詳細
Glucose transporter 1 (GLUT1, SLC2A1) belongs to the family of glucose transporters (GLUTs). It is localized to the membrane and is highly expressed in the brain and spinal cord, with a relative high density in the cerebellum. The vascular form of GLUT1 is mainly localized in endothelial cells of blood vessels.
免疫原
peptide corresponding to a sequence at the C-terminus of human GLUT1, conjugated to KLH. The corresponding sequence is identical in rat and mouse GLUT1.
アプリケーション
Anti-GLUT1 (C-terminal) antibody produced in rabbit has been used in immunoblotting.
生物化学的／生理学的作用
GLUT1 is the main glucose transporter in the blood-brain barrier (BBB), which regulates basal glucose levels. Increased expression of GLUT1 is associated with cell growth and in malignant transformation.
物理的形状
solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SAB4200519-200UL:
SAB4200519-BULK:
SAB4200519-VAR:
IXO15354:
最新バージョンのいずれかを選択してください：
Differential localization of glucose transporter isoforms in non-polarized mammalian cells: distribution of GLUT1 but not GLUT3 to detergent-resistant membrane domains
Sakyo T and Kitagawa T
Biochimica et Biophysica Acta - Biomembranes, 1567, 165-175 (2002)
Photobiomodulatory effects of superpulsed 904 nm laser therapy on bioenergetics status in burn wound healing
Yadav A, et al.
Journal of Photochemistry and Photobiology. B, Biology, 162, 77-85 (2016)
Immunohistochemical localization and quantification of glucose transporters in the mouse brain
Choeiri C, et al.
Neuroscience, 111(1), 19-34 (2002)
Glucose transporters: expression, regulation and cancer
Medina RA and Owen GI
Biological Research, 35(1), 9-26 (2002)
Aarón Guerrero et al.
Frontiers in cardiovascular medicine, 8, 644797-644797 (2021-06-29)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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