SAB4200806

Anti-Ezrin antibody, Mouse monoclonal

clone 3C12, purified from hybridoma cell culture

• 別名: Cytovillin, Villin-2, p81
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: 3C12, monoclonal
• 形状: buffered aqueous solution
• 分子量: ~80 kDa
• 化学種の反応性: bovine, canine, hamster, kangaroo, human, monkey, rat, mouse
• 包装: antibody small pack of 25 μL
• 濃度: ~1 mg/mL
• テクニック: immunoblotting: 1-2 μg/mL using using canine MDCK cells extract; immunofluorescence: 0.5-1 μg/mL using human epidermoid carcinoma A431 cells.
• アイソタイプ: IgG1
• UniProtアクセッション番号: P15311
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Ezr(22350)

詳細

詳細

Ezrin, also known as cytovillin, p81 or 80K, is a.member of the ERM proteins family composed of Ezrin, Radixin, and Moesin. These proteins are known as actin-binding proteins that link the cell membrane to the actin cytoskeleton, particularly in microvillus-bearing epithelial cells. Ezrin is present in microvilli, microspikes, and membrane ruffles of cells.
The ERM proteins family are involved in the functional expression of membrane proteins on the cell surface, integrate Rho guanosine 5′-triphosphatase (GTPase) signaling regulating cytoskeletal organization and act as protein kinase A (PKA)-anchoring proteins. Therefore, ERM proteins seem to play an important role in the membrane transport of electrolytes by ion channels and transporters.

免疫原

The carboxy-terminal part of recombinant human ezrin

アプリケーション

Monoclonal Anti-Ezrin recognizes an epitope located on the C-terminal region of Ezrin. Reactivity has been observed with human, mouse, hamster, monkey, bovine, canine, rat and rat-kangaroo origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~80kDa), immunofluorescence, Immunohistochemistry and immunoprecipitation.

物理的形状

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.

その他情報

This product is for R&D use only, not for drug, household, or other uses.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable