SAB4501220

Anti-GLP1R antibody produced in rabbit

affinity isolated antibody

• 別名: GLP-1 receptor, GLP-1-R, GLP-1R, GLP1R, Glucagon-like peptide 1 receptor
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA; IF
• クローン: polyclonal
• 化学種の反応性: human, mouse
• citations: 2
• テクニック: ELISA: 1:5000; immunofluorescence: 1:100-1:500

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 53 kDa
• 化学種の反応性: human, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:5000; immunofluorescence: 1:100-1:500
• NCBIアクセッション番号: P43220
• UniProtアクセッション番号: P43220
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GLP1R(2740)

詳細

詳細

Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.

Glucagon-like peptide 1 receptor (GLP1R) protein belongs to the class B G protein-coupled receptor (GPCR) secretin family. This classic seven-transmembrane protein is abundantly expressed in the cardiovascular system. The GLP1R gene is located on the human chromosome 6p21. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.

免疫原

The antiserum was produced against synthesized peptide derived from human GLP1R.

Immunogen Range: 101-150

アプリケーション

Anti-GLP1R antibody produced in rabbit has been used in immunofluorescence staining.

生物化学的／生理学的作用

Glucagon-like peptide 1 receptor (GLP1R) protein participates in the activation of protein kinase A (PKA), phosphoinositide 3-kinase (PI3K), MEK1/2, and endothelial nitric oxide synthase (eNOS) pathways. Hence, it plays a key role in apoptosis reduction, improved energy metabolism, decreased inflammation in myocardial cells, and vasodilation in myocardial arteries. The large N-terminal extracellular domain of GLP1R participates in ligand binding. Alterations in the GLP1R gene might increase the risk of coronary artery disease (CAD).

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable