SAB4503479
Anti-FGF18 antibody produced in rabbit
affinity isolated antibody
別名:
FGF-18
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すべての画像(2)
About This Item
UNSPSCコード:
12352203
NACRES:
NA.41
結合体:
unconjugated
application:
ELISA
IF
IHC
IF
IHC
クローン:
polyclonal
化学種の反応性:
human
citations:
4
テクニック:
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 23 kDa
化学種の反応性
human
濃度
~1 mg/mL
テクニック
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... FGF18(8817)
詳細
Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human FGF18.
Immunogen Range: 151-200
Immunogen Range: 151-200
生物化学的／生理学的作用
FGF18 (fibroblast growth factor 18) plays an important role in the skeletal development of the embryonic and adult organism. It is associated with colorectal and ovarian cancer. FGF18 participates in cell proliferation and differentiation during osteogenesis and chondrogenesis. It is essential for the growth of bone, cartilage, hair, cardiovasculature and alveolus.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
The crystal structure of fibroblast growth factor 18 (FGF18).
Alan B, et al.
Protein & cell, 5(5), 343?347-343?347 (2014)
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
Ohbayashi N, et al.
Genes & Development, 16(7), 870-879 (2002)
Wei Wei et al.
The Journal of clinical investigation, 123(10), 4435-4448 (2013-09-11)
High-throughput genomic technologies have identified biomarkers and potential therapeutic targets for ovarian cancer. Comprehensive functional validation studies of the biological and clinical implications of these biomarkers are needed to advance them toward clinical use. Amplification of chromosomal region 5q31-5q35.3 has
Nobuyuki Itoh et al.
Trends in genetics : TIG, 20(11), 563-569 (2004-10-12)
Fibroblast growth factors (Fgfs) and Fgf receptors (Fgfrs) comprise a signaling system that is conserved throughout metazoan evolution. Twenty-two Fgfs and four Fgfrs have been identified in humans and mice. During evolution, the Fgf family appears to have expanded in
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