おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 48 kDa
交差性
rat, human, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CCNB1(891)
詳細
Anti-Cyclin B1 Antibody detects endogenous levels of total Cyclin B1 protein.
Cyclin B1 belongs to the cyclin family. It is a 48.337kDa protein. It is present in low level in testis, thymus, bone marrow and smooth muscle. It is mapped to human chromosome 5q13.2.
免疫原
The antiserum was produced against synthesized peptide derived from human Cyclin B1.
Immunogen Range: 91-140
Immunogen Range: 91-140
アプリケーション
Anti-Cyclin B1 antibody has been used in western-blot analysis.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生物化学的／生理学的作用
Cyclin B1-CDK1 (cyclin-dependent kinase 1) helps to induce chromosome condensation, nuclear lamina resolution and mitotic spindle assembly. It also acts as a potential target for a cancer vaccine.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
CCNB1 (cyclin B1)
Perez-Stable C
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain
Chen Y, et al.
Oncotarget, 8(1), 1234-1246 (2017)
Yu-Jie Wu et al.
Journal of cell science, 134(9) (2021-05-12)
Multiciliated cells (MCCs) are terminally differentiated postmitotic cells that possess hundreds of motile cilia on their apical surface. Defects in cilia formation are associated with ciliopathies that affect many organs. In this study, we tested the role and mechanism of
The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors
Chevaleyre C, et al.
Journal of Immunology, 195(4), 1891-1901 (2015)
Praveen Kumar Reddy Nagireddy et al.
ACS omega, 4(21), 19382-19398 (2019-11-26)
Noscapine, a phthalide isoquinoline alkaloid isolated from the opium poppy Papaver somniferum, is traditionally being used as an anticough drug. With a safe in vitro toxicological profile, noscapine and its analogues have been explored to show microtubule-regulating properties and anticancer
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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