SAB5702250

Anti-CLDN18.2 Antibody, clone 3J4G7, Rabbit Monoclonal

• 別名: CLDN18,SFTA5,SFTPJ
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 3J4G7, monoclonal
• 形状: liquid
• 化学種の反応性: human
• 濃度: 1.191 mg/mL
• テクニック: immunohistochemistry: 1:50 - 1:200
• 色: colorless
• アイソタイプ: IgG
• UniProtアクセッション番号: P56856
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CLDN18.2(51208)

詳細

詳細

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

免疫原

A synthetic peptide of human CLDN18.2.

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

IHC

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H317,H411
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 2 - Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3