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製品名
Anti-alpha + beta Synuclein Antibody, clone 9E9X5, Rabbit Monoclonal,
由来生物
rabbit
品質水準
物質
colorless
クローン
9E9X5, monoclonal
フォーム
liquid
分子量
18 kDa
交差性
human, rat, rat
濃度
1.35 mg/mL
テクニック
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
色
colorless
アイソタイプ
IgG
免疫原配列
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQL
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SNCA(6620) , SNCB(6622)
詳細
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human alpha + beta Synuclein (P37840).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
アプリケーション
WB, IF/ICC
保管分類コード
10 - Combustible liquids
WGK
WGK 1
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