SML1252

Treosulfan

≥98% (HPLC)

• 別名: (2S,3S)-Butanetetraol 1,4-dimesylate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threitol 1,4-bis(methanesulfonate), NSC 39069, Threosulphan, Treosulphan
• 実験式（ヒル表記法）: C₆H₁₄O₈S₂
• CAS番号: 299-75-2
• 分子量: 278.30
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 光学活性: [α]/D -4.9 to -5.9°, c = 1 in acetone
• 色: white to beige
• 溶解性: H₂O: 5 mg/mL, clear
• 保管温度: −20°C
• SMILES記法: [S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C
• InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
• InChI Key: YCPOZVAOBBQLRI-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Treosulfan is a biofunctional alkylating agent.

Treosulfan is bifunctional alkylating agent.

Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H340,H350,H361f
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Carc. 1A - Muta. 1B - Repr. 2
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable