SML3128

HU-308

≥98% (HPLC)

• 別名: (1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol, HU308
• 実験式（ヒル表記法）: C₂₇H₄₂O₃
• CAS番号: 256934-39-1
• 分子量: 414.62
• MDL番号: MFCD23102377
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 光学活性: [α]/D 180.0 to 130.0°, c = 0.5 in chloroform-d
• 保管条件: desiccated
• 色: white to dark beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: −20°C
• SMILES記法: CCCCCCC(C)(C1=CC(OC)=C(C(OC)=C1)[C@]2(C=C([C@@H]3C(C)([C@H]2C3)C)CO)[H])C
• InChI: 1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21+,22-/m0/s1
• InChI Key: CFMRIVODIXTERW-BDTNDASRSA-N

詳細

生物化学的／生理学的作用

HU-308 is a potent, selective agonist of the cannabinoid receptor CB2. The Ki values for CB2 vs. CB1 are 22.7nM and >10 mM, respectively. HU-308 has anti-inflammatory and neuroprotective properties, and reduces liver damage in a hepatic ischemia/reperfusion injury model.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable