SRP6007

NT-3 マウス由来

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

• 別名: HDNF, NGF-2, NT-3, 神経成長因子-2, 神経栄養因子
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: mouse
• リコンビナント: expressed in E. coli
• アッセイ: ≥97% (HPLC); ≥97% (SDS-PAGE)
• 形状: lyophilized
• 分子量: 13.6 kDa
• 包装: pkg of 10 μg
• 不純物: Endotoxin, tested
• NCBIアクセッション番号: P20181
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... NTF3(18205)

詳細

詳細

NT-3 (neurotrophin-3) is a member of the family of trophic factors, called neurotrophins. This family also includes NGF (nerve growth factor), BDNF (brain-derived neurotrophic factor), and NT-4. NT-3 is the most abundantly expressed neurotrophin during early development.
Murine NT-3 produced from Escherichia coli contains 119 amino acid and having a molecular mass is 13.6kDa.

アプリケーション

NT-3 (neurotrophin-3) has been used for the ex vivo treatment of skin punches obtained from rat and human samples.

生物化学的／生理学的作用

Study in mice show that NT-3 (neurotrophin-3), along with BDNF (brain-derived neurotrohpic factor), is essential for inner ear development. In vitro motor, enteric, primary sensory, sympathetic, locus coeruleus, cerebellar and hippocampal neurons are responsive to NT-3. Mice null for NT-3 show significant deficiency in sympathetic and sensory nerve populations. In mice, post birth up-regulation of NT-3 induces a second wave of dopaminergic amacrine cell genesis.

物理的形状

Sterile filtered and lyophilized powder

再構成

Centrifuge the vial prior to opening. Reconstitute in H?O to a concentration of 0.1-1.0 mg/ml.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable