추천 제품
vapor pressure
4 mmHg ( 83 °C)
Quality Level
분석
98%
형태
liquid
refractive index
n20/D 1.551 (lit.)
bp
105-106 °C/22 mmHg (lit.)
130-135 °C/90 mmHg (lit.)
density
1.303 g/mL at 25 °C (lit.)
작용기
acyl chloride
저장 온도
2-8°C
SMILES string
ClC(=O)Cc1cccs1
InChI
1S/C6H5ClOS/c7-6(8)4-5-2-1-3-9-5/h1-3H,4H2
InChI key
AJYXPNIENRLELY-UHFFFAOYSA-N
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애플리케이션
2-Thiopheneacetyl chloride was used in the synthesis of:
- (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate, nipecotate-containing immunopotentiator
- 5-fluorouracil-cephalosporin prodrug
- series of new N,N′-di(thiopheneacetyl)diamines derivatives
- 6-β-(thiophen-2′-yl)acetamidomorphine
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point (°F)
215.6 °F - closed cup
Flash Point (°C)
102 °C - closed cup
개인 보호 장비
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
이미 열람한 고객
Bioorganic & medicinal chemistry, 12(22), 5983-5990 (2004-10-23)
A series of 6-beta-arylamidomorphines was synthesized and biologically evaluated. Various aryl substituents were introduced into the arylamidomorphines to examine substituent structure-activity relationships. Competition binding assays showed that compounds 10a-h bound to the mu opioid receptor with high affinity (0.2-0.6 nM).
Development of an efficient synthesis for a nipecotate-containing immunopotentiator.
Organic Process Research & Development, 8(4), 593-596 (2004)
Synthesis and Biological Evaluation of N, N'-di (thiopheneacetyl) diamines Series as Antitubercular Agents.
Phosphorus, Sulfur, and Silicon and the Related Elements, 183(12), 2990-2997 (2008)
Bioorganic & medicinal chemistry letters, 19(4), 1261-1263 (2009-01-27)
An efficient synthesis of a 5-fluorouracil-cephalosporin prodrug is described for use against colorectal and other cancers in antibody and gene-directed therapies. The compound shows stability in aqueous media until specifically activated by beta-lactamase (betaL). The kinetic parameters of the 5-fluorouracil-cephalosporin
Bioorganic & medicinal chemistry, 22(17), 4968-4997 (2014-07-22)
TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido moieties at
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