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Merck
모든 사진(3)

주요 문서

219096

Sigma-Aldrich

D-Aspartic acid

99%, for peptide synthesis, ReagentPlus®

동의어(들):

(R)-(−)-Aminosuccinic acid, (R)-2-Aminosuccinic acid

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About This Item

Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
133.10
Beilstein:
1723529
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.22

제품명

D-Aspartic acid, ReagentPlus®, 99%

Quality Level

제품 라인

ReagentPlus®

분석

99%

양식

powder

광학 활성

[α]20/D −24°, c = 2.3 in 6 M HCl

광학 순도

ee: 98% (GLC)

반응 적합성

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

응용 분야

peptide synthesis

SMILES string

N[C@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

InChI key

CKLJMWTZIZZHCS-UWTATZPHSA-N

유전자 정보

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애플리케이션


  • Metabolomics Analysis Identifies Differential Metabolites as Biomarkers for Acute Myocardial Infarction.: This study utilizes metabolomics to identify biomarkers for acute myocardial infarction, showcasing D-Aspartic acid′s role in amino acid metabolism and potential diagnostic applications. (Zhou et al., 2024).

법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Francesco Errico et al.
Amino acids, 43(5), 1861-1871 (2012-08-02)
Free D-aspartate (D-Asp) occurs in substantial amounts in the brain at the embryonic phase and in the first few postnatal days, and strongly decreases in adulthood. Temporal reduction of D-Asp levels depends on the postnatal onset of D-aspartate oxidase (DDO)
Antimo D'Aniello
Brain research reviews, 53(2), 215-234 (2006-11-23)
D-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. During the embryonic stage of birds and the early postnatal
H Homma
Amino acids, 32(1), 3-11 (2006-06-07)
Recent investigations have shown that D-aspartate (D-Asp) plays an important physiological role(s) in the mammalian body. Here, several recent studies of free D-Asp metabolism in mammals, focusing on cellular localization in tissues, intracellular localization, biosynthesis, efflux, uptake and degradation are
Ikuhiko Noji et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3310-3316 (2011-07-12)
Unusual amino acid residues such as L-β-aspartyl (Asp), D-α-Asp, and D-β-Asp have been detected in proteins and peptides such as α-crystallin in the lens and β-amyloid in the brain. These residues increase with age, and hence they are associated with
Yuhei Mori et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3303-3309 (2011-06-04)
UV-B irradiation is one of the risk factors in age-related diseases. We have reported that biologically uncommon D-β-Asp residues accumulate in proteins from sun-exposed elderly human skin. A previous study also reported that carboxymethyl lysine (CML; one of the advanced

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