230995

2-(2-Bromoethyl)-1,3-dioxolane

96%

• 동의어(들): 3-Bromopropionaldehyde ethylene acetal
• 실험식(Hill 표기법): C₅H₉BrO₂
• CAS Number: 18742-02-4
• Molecular Weight: 181.03
• Beilstein: 103516
• EC Number: 242-551-1
• MDL number: MFCD00003216
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24853846
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 96%
• 양식: liquid
• 포함: sodium bicarbonate as stabilizer
• refractive index: n20/D 1.479 (lit.)
• bp: 68-70 °C/8 mmHg (lit.)
• density: 1.542 g/mL at 25 °C (lit.)
• 작용기: bromo; ether
• 저장 온도: 2-8°C
• SMILES string: BrCCC1OCCO1
• InChI: 1S/C5H9BrO2/c6-2-1-5-7-3-4-8-5/h5H,1-4H2
• InChI key: GGZQLTVZPOGLCC-UHFFFAOYSA-N

설명

일반 설명

Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.

2-(2-Bromoethyl)-1,3-dioxolane is a cyclic ether derivative with a dioxolane ring, used as a building block in organic synthesis and polymer industry.

애플리케이션

2-(2-Bromoethyl)-1,3-dioxolane was used:

• as starting reagent for the synthesis of (5Z,9Z)-5,9-hexadecadienoic acid, (5Z,9Z)-5,9-nonadecadienoic acid and (5Z,9Z)-5,9-eicosadienoic acid
• in synthesis of 1-deoxy-castanospermine and 1-deoxy-8a-epi-castanospermine
• in asymmetric total synthesis of both enantiomers of marine mollusk metabolite pulo′upone via Evans′ asymmetric Diels-Alder reaction
• as alkylating agent for amines, dithianes and carboximides
• with eynamides and sodium azide in a "one-pot" synthesis of triazoles

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point (°F): 149.0 °F - closed cup
• Flash Point (°C): 65 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter