323322

Trimethylphosphine

97%

• 동의어(들): PMe₃
• Linear Formula: (CH₃)₃P
• CAS Number: 594-09-2
• Molecular Weight: 76.08
• Beilstein: 969138
• EC Number: 209-823-1
• MDL number: MFCD00008510
• UNSPSC 코드: 12352128
• PubChem Substance ID: 24859357
• NACRES: NA.22

속성

• vapor pressure: 7.24 psi ( 20 °C)
• Quality Level: 200
• 분석: 97%
• 형태: liquid
• 반응 적합성: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Mitsunobu Reaction; reagent type: ligand; reaction type: Wittig Reaction
• refractive index: n20/D 1.428 (lit.)
• bp: 38-40 °C (lit.)
• mp: −86 °C (lit.)
• density: 0.738 g/mL at 20 °C (lit.)
• 작용기: phosphine
• 저장 온도: 2-8°C
• SMILES string: CP(C)C
• InChI: 1S/C3H9P/c1-4(2)3/h1-3H3
• InChI key: YWWDBCBWQNCYNR-UHFFFAOYSA-N

설명

애플리케이션

Trimethylphosphine (PMe₃) is an electron-rich phosphine ligand used as a reagent in Mitsunobu reaction.
It can be used:

• In transformation of azides into carbamates; aziridines to azidoalcohols; and ketoximes to ketones with 2,2′-dipyridyl diselenide.
• In Aza-Wittig reaction;, C-H bond activation of imines; cross-coupling reactions.
• In the preparation of (cyanomethylene) trimethylphosphorane (CMMP) which is used as a reagent in Mitsunobu type reaction.
• As a reagent in the synthesis of ruthenium trimethylphosphine complexes, which in turn are used as catalysts for hydrogenation of CO₂ to formic acid.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H315,H319,H335
• 예방조치 성명서: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): -2.2 °F - closed cup
• Flash Point (°C): -19 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves