347817

Trifluoromethanesulfonic acid

ReagentPlus^®, ≥99%

• 동의어(들): Triflic acid
• Linear Formula: CF₃SO₃H
• CAS Number: 1493-13-6
• Molecular Weight: 150.08
• Beilstein: 1812100
• EC Number: 216-087-5
• MDL number: MFCD00007514
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24861529
• NACRES: NA.22

속성

• Grade: reagent grade
• Quality Level: 200
• vapor density: 5.2 (vs air)
• vapor pressure: 8 mmHg ( 25 °C)
• 제품 라인: ReagentPlus^®
• 분석: ≥99%
• 양식: liquid
• refractive index: n20/D 1.327 (lit.)
• bp: 162 °C (lit.)
• mp: - 40 °C
• solubility: 1,600 g/L at 20 °C
• density: 1.696 g/mL at 25 °C (lit.)
• 작용기: fluoro; triflate
• SMILES string: OS(=O)(=O)C(F)(F)F
• InChI: 1S/CHF3O3S/c2-1(3,4)8(5,6)7/h(H,5,6,7)
• InChI key: ITMCEJHCFYSIIV-UHFFFAOYSA-N

설명

일반 설명

Trifluoromethanesulfonic acid is a strong organic acid. It can be prepared by reacting bis(trifluoromethylthio)mercury with H₂O₂. On mixing with HNO₃, it affords a nitrating reagent (a nitronium salt). This reagent is useful for the nitration of aromatic compounds. Its dissociation in various organic solvents has been studied.

애플리케이션

Deglycosylation agent

Trifluoromethanesulfonic acid can be used as a catalyst to prepare:

• Substituted tetrahydrofurans and tetrahydropyrans by cyclization of corresponding unsaturated alcohols under acidic conditions.
• Nitriles from corresponding aldehydes by Schmidt reaction.
• Disubstituted five-membered ring lactones by allylboration reaction between 2-alkoxycarbonyl allylboronates and aldehydes.

It can also be used as a catalyst in the Fischer glycosylation and Friedel-Crafts acylation reactions.

법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H290,H302,H314,H335
• 예방조치 성명서: P234 - P261 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point (°F): >332.1 °F - Pensky-Martens closed cup
• Flash Point (°C): > 166.7 °C - Pensky-Martens closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter