158534

Trifluoromethanesulfonic acid

reagent grade, 98%

• 동의어(들): TFMSA, Triflic acid
• Linear Formula: CF₃SO₃H
• CAS Number: 1493-13-6
• Molecular Weight: 150.08
• Beilstein: 1812100
• EC Number: 216-087-5
• MDL number: MFCD00007514
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24849764
• NACRES: NA.21

속성

• Grade: reagent grade
• Quality Level: 200
• vapor density: 5.2 (vs air)
• vapor pressure: 8 mmHg ( 25 °C)
• 분석: 98%
• 양식: liquid
• refractive index: n20/D 1.327 (lit.)
• bp: 162 °C (lit.)
• density: 1.696 g/mL at 25 °C (lit.)
• 작용기: fluoro; triflate
• SMILES string: OS(=O)(=O)C(F)(F)F
• InChI: 1S/CHF3O3S/c2-1(3,4)8(5,6)7/h(H,5,6,7)
• InChI key: ITMCEJHCFYSIIV-UHFFFAOYSA-N

설명

일반 설명

Trifluoromethanesulfonic acid is the strongest monoprotic organic acid. It has been synthesized by the oxidation of bis(trifluoromethylthio)mercury with aqueous hydrogen peroxide. It undergoes complete dissociation in basic solvents such as dimethyl sulfoxide, dimethylacetamide and dimethylformamide. Its dissociation in non-aqueous solvents has been studied by conductometry. On mixing trifluoromethanesulfonic acid with HNO_3, it forms nitronium trifluoromethane sulfonate, which is an excellent nitrating reagent.

애플리케이션

Deglycosylation agent

Trifluoromethanesulfonic acid is a versatile reagent, employed as catalyst for the following studies:

• Friedel-Crafts acylation of aromatic compounds with methyl benzoate.
• Addition reaction of dialkyl disulfides to terminal alkynes.
• Synthesis of a single cyclic tetrasiloxane containing propylammonium trifluoromethanesulfonate and methyl side-chain groups (Am-CyTS).
• Preparation of starting reagents for the synthesis of fluorinated 2,5-substituted 1-ethyl-1H-benzimidazole derivatives.
• Synthesis of aryl triflates, the lactonization of alkenoic acids, and the formation of E-alkenes.

Trifluoromethanesulfonic acid may be used as an initiator for the cationic polymerization of styrene, hexamethylcyclotrisiloxane and L,L-dilactide.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H290,H302,H314,H335
• 예방조치 성명서: P234 - P261 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point (°F): >332.1 °F - Pensky-Martens closed cup
• Flash Point (°C): > 166.7 °C - Pensky-Martens closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter