374318

Dimethyl (S)-(−)-malate

98%

• 동의어(들): Dimethyl (S)-2-hydroxysuccinate, Dimethyl L-malate
• Linear Formula: CH₃O₂CCH₂CH(OH)CO₂CH₃
• CAS Number: 617-55-0
• Molecular Weight: 162.14
• Beilstein: 1724363
• EC Number: 432-310-0
• MDL number: MFCD00066215
• UNSPSC 코드: 12352108
• PubChem Substance ID: 24863298
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 98%
• 광학 활성: [α]20/D −6.5°, neat
• refractive index: n20/D 1.435 (lit.)
• density: 1.223 g/mL at 25 °C (lit.)
• 작용기: ester; hydroxyl
• 저장 온도: 2-8°C
• SMILES string: COC(=O)C[C@H](O)C(=O)OC
• InChI: 1S/C6H10O5/c1-10-5(8)3-4(7)6(9)11-2/h4,7H,3H2,1-2H3/t4-/m0/s1
• InChI key: YSEKNCXYRGKTBJ-BYPYZUCNSA-N

설명

애플리케이션

Dimethyl (S)-(-)-malate may be used as a starting material to synthesize (-)-tulipalin B. The selective reduction of its ester group to alcohol can be accomplished using borane-dimethyl sulfide complex (BMS) in the presence of sodium tetrahydroborate.

This chiral synthon has been used to prepare cytochrome P450 metabolites of arachidonic acid, and cyclic sulfolanes with HIV-1 protease inhibition potential.

안전성 정보

• 픽토그램: GHS02,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H226,H317,H318
• 예방조치 성명서: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 3 - Skin Sens. 1
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 131.0 °F
• Flash Point (°C): 55 °C
• 개인 보호 장비: Eyeshields, Gloves