392715

N-Fluorobenzenesulfonimide

97%

• 동의어(들): N-Fluorodi(benzenesulfonyl)amine, N-Fluorodibenzenesulfonimide, NFSI
• Linear Formula: (C₆H₅SO₂)₂NF
• CAS Number: 133745-75-2
• Molecular Weight: 315.34
• Beilstein: 5348902
• MDL number: MFCD00144885
• UNSPSC 코드: 12352101
• PubChem Substance ID: 24864479
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• 양식: powder
• mp: 110 °C (dec.) (lit.)
• SMILES string: FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c2ccccc2
• InChI: 1S/C12H10FNO4S2/c13-14(19(15,16)11-7-3-1-4-8-11)20(17,18)12-9-5-2-6-10-12/h1-10H
• InChI key: RLKHFSNWQCZBDC-UHFFFAOYSA-N

설명

일반 설명

N-Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions.
NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine.

애플리케이션

Reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. Also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.

Stable, easy-to-handle, crystalline material which readily transfers F⁺ to enolates and carbanions.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves