39410

4-(Dimethylamino)pyridine, polymer-bound

extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB

• 동의어(들): 4-(Dimethylamino)pyridine on Polystyrene, DMAP on PS, polymer bound DMAP
• 실험식(Hill 표기법): C₈H₈
• CAS Number: 82942-26-5
• Molecular Weight: 104.15
• MDL number: MFCD04041220
• UNSPSC 코드: 12352128
• PubChem Substance ID: 57649897
• NACRES: NA.22

속성

• 반응 적합성: reaction type: solution phase peptide synthesis
• 라벨링 범위: ~3.0 mmol/g "DMAP" loading
• 기질: crosslinked with 2% DVB
• 음이온 미량물: chloride (Cl^-): ≤5000 mg/kg

설명

일반 설명

Polymer-bound 4-(dimethylamino)pyridine is used for improved derivatization of chiral and achiral aliphatic amines, amino alcohols and amino acids.

애플리케이션

Polymer-bound 4-(dimethylamino)pyridine is used as a supported base in the Michael addition and nitrous acid elimination process step involved in the synthesis of thiophene-2-carboxylates using β-nitroacrylates as starting materials, under a general and efficient continuous flow-based protocol. It also serves as a supported catalyst in the preparation of ω-nitro esters starting from cyclic 2-nitro ketones under solid heterogeneous catalysis.(5)

기타 정보

Polymer supported, recyclable acylation catalyst

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)