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![4-[(N-Boc)aminomethyl]aniline 97%](/deepweb/assets/sigmaaldrich/product/structures/341/155/530c425c-7e6e-435e-a28a-9d40b05b938a/640/530c425c-7e6e-435e-a28a-9d40b05b938a.png)
Quality Level
분석
≥98.0% (HPLC)
반응 적합성
reagent type: cross-linking reagent
작용기
Boc
amine
SMILES string
NC1=CC(NC(OC(C)(C)C)=O)=CC=C1
InChI
1S/C11H16N2O2/c1-11(2,3)15-10(14)13-9-6-4-5-8(12)7-9/h4-7H,12H2,1-3H3,(H,13,14)
InChI key
IEUIEMIRUXSXCL-UHFFFAOYSA-N
애플리케이션
N-Boc-m-phenylenediamine (tert-Butyl-3-aminophenylcarbamate) may be used in the preparation of:
- 5,5′-(propane-2,2-diyl)bis(N-(3-aminophenyl)-4-methyl-3-phenyl-1H-pyrrole-2-carboxamide)
- ethyl 4-[{3-[(tert-butoxycarbonyl)amino]phenyl}amino]-2-chloropyrimidine-5-carboxylate
- ethyl 4-(3-(tert-butoxycarbonyl)phenylamino)-2-(methylthio)pyrimidine-5-carboxylate
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Pyrimido [4,5-d] pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790 to Methionine790 (T790M) Mutants.
Xu T, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 125(32), 8545-8548 (2013)
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine790? methionine790 mutant.
Chang S, et al.
Journal of Medicinal Chemistry, 55(6), 2711-2723 (2012)
Grigory V Kolesnikov et al.
Organic & biomolecular chemistry, 9(21), 7358-7364 (2011-09-07)
The design and synthesis of a neutral macrocyclic host that is capable of perrhenate and pertechnetate recognition is described. The anion affinities and underlying coordination modes were estimated by several experimental and theoretical methods including a new technique--reverse (99)Tc NMR
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