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Key Documents

692905

Sigma-Aldrich

N-Ethyl-d5-maleimide

99 atom % D, 98% (CP)

동의어(들):

NEM (ethyl-d5)

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About This Item

실험식(Hill 표기법):
C6D5H2NO2
CAS Number:
Molecular Weight:
130.16
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.13

동위원소 순도

99 atom % D

Quality Level

분석

98% (CP)

형태

powder

mp

43-46 °C (lit.)

질량 이동

M+5

저장 온도

2-8°C

SMILES string

[2H]C([2H])([2H])C([2H])([2H])N1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3/i1D3,2D2

InChI key

HDFGOPSGAURCEO-ZBJDZAJPSA-N

일반 설명

N-Ethyl-d5-maleimide is a deuterated isotope analog of N-ethymaleimide, wherein methylene and methyl protons are replaced by deuterium.

애플리케이션

N-Ethyl-d5-maleimide can be used:
  • To synthesize isotopic silica nanotag by reacting with silica precursor 3-mercaptopropyltrimethoxysilane (MPTMS) for multiplexed ion beam imaging.
  • As an isotopic internal standard to determine the ratio of glutathione (GSH) and glutathione disulfide (GSSG) in cultured cells using HPLC-UV and LC-QTOF-MS.

포장

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

픽토그램

Skull and crossbonesCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

163.4 °F - closed cup

Flash Point (°C)

73 °C - closed cup


시험 성적서(COA)

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문서 라이브러리 방문

Stefan Harmsen et al.
Advanced materials technologies, 5(7) (2020-07-15)
High-dimensional profiling of markers and analytes using approaches, such as barcoded fluorescent imaging with repeated labeling and mass cytometry has allowed visualization of biological processes at the single-cell level. To address limitations of sensitivity and mass-channel capacity, a nanobarcoding platform
Xueni Sun et al.
Metabolites, 10(7) (2020-07-28)
Glutathione (GSH) and glutathione disulfide (GSSG) are commonly used to assess the oxidative status of a biological system. Various protocols are available for the analysis of GSH and GSSG in biomedical specimens. In this study, we present an optimized protocol
Isotopically Encoded Nanotags for Multiplexed Ion Beam Imaging
Harmsen S, et al.
Advanced Materials Technologies, 5(7), 2000098-2000098 (2020)
Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS
Sun X, et al.
Metabolites, 10(7), 292-292 (2020)
Benjamin Neuditschko et al.
Molecular & cellular proteomics : MCP, 19(3), 478-489 (2020-01-02)
The prediction of metastatic properties from molecular analyses still poses a major challenge. Here we aimed at the classification of metastasis-related cell properties by proteome profiling making use of cutaneous and brain-metastasizing variants from single melanomas sharing the same genetic

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