775797

Isopropylmagnesium bromide solution

0.75 M in THF

• 동의어(들): 1-Methylethylmagnesium bromide, 2-Propylmagnesium bromide, iso-Propylmagnesium bromide, Bromoisopropylmagnesium
• Linear Formula: (CH₃)₂MgBr
• CAS Number: 920-39-8
• Molecular Weight: 147.30
• MDL number: MFCD00672110
• UNSPSC 코드: 12352103
• PubChem Substance ID: 329767789
• NACRES: NA.22

속성

• 형태: solution
• 반응 적합성: reaction type: Grignard Reaction
• 농도: 0.75 M in THF
• density: 0.982 g/mL at 25 °C
• 저장 온도: 2-8°C
• SMILES string: CC(C)[Mg]Br
• InChI: 1S/C3H7.BrH.Mg/c1-3-2;;/h3H,1-2H3;1H;/q;;+1/p-1
• InChI key: UCJIVFREPMUZDC-UHFFFAOYSA-M

설명

애플리케이션

• Preparation of isopropylmagnesium bromide solutions: In this study, various concentrations of isopropylmagnesium bromide solutions were prepared, detailing their stability and reactivity for use in palladium-catalyzed cross-coupling reactions and other synthetic applications (Vulović et al., 2017).
• Reductive coupling of amides: This research discusses the reductive functionalization of tertiary amides using isopropylmagnesium bromide, providing a novel method for amine synthesis, which is crucial for pharmaceutical chemistry (Xie and Dixon, 2017).
• Synthesis of 1, 2, 3-triazoles: The study explores the use of isopropylmagnesium bromide in the synthesis of 1, 2, 3-triazoles through Grignard reactions, highlighting its role in protecting azides during the reaction process (Namioka et al., 2023).
• Disposable cartridge concept for Grignard reagents: This paper introduces a novel disposable cartridge for the on-demand synthesis of Grignard reagents, including isopropylmagnesium bromide, enhancing the safety and scalability of Grignard reactions (Berton et al., 2020).

포장

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

법적 정보

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• 픽토그램: GHS02,GHS08,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H260,H302,H314,H335,H336,H351
• 예방조치 성명서: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• 표적 기관: Respiratory system
• 보충제 위험성: EUH014,EUH019
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 1
• Flash Point (°F): -22.0 °F - closed cup
• Flash Point (°C): -30 °C - closed cup