910015

17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid

≥95%

• 동의어(들): Azido-PEG₅-CH₂CO₂H, Azido-PEG₅-acid, N₃-PEG₅-CH₂COOH
• 실험식(Hill 표기법): C₁₂H₂₃N₃O₇
• CAS Number: 217180-81-9
• Molecular Weight: 321.33
• MDL number: MFCD31561141
• UNSPSC 코드: 12352106

속성

• 분석: ≥95%
• 양식: (Liquid or Semi-solid or Paste or Solid)
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent
• 작용기: azide; carboxylic acid
• 저장 온도: 2-8°C
• SMILES string: OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O

설명

애플리케이션

This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG₅-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

기타 정보

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

법적 정보

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable