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Merck
모든 사진(3)

주요 문서

912220

Sigma-Aldrich

NanoFabTx PLGA-micro

for synthesis of 1-5 μm particles

동의어(들):

NanoFabTx reagent kit, PLGA microparticle kit

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About This Item

UNSPSC 코드:
12161503
NACRES:
NA.23

Quality Level

응용 분야

advanced drug delivery

저장 온도

2-8°C

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일반 설명

The NanoFabTx PLGA-micro kit provides reagents (PLGA and stabilizer) and a protocol for microfluidic synthesis of microparticles between 1 to 5 μm. This reagent kit can be combined with the NanoFabTx Microfluidic - micro device kit (Cat.No. 911860) for microfluidic synthesis of PLGA micro particles.

애플리케이션

NanoFabTx PLGA-micro for synthesis of 1-5 μm particle reagent kit is designed for the synthesis of hydrophobic drug- encapsulated poly(lactic-co-glycolic acid) (PLGA) microparticles. The protocol gives users step-by-step instructions developed and tested by our formulation scientists. The protocol includes suggested conditions for incorporating drugs into the formulation and details how to tailor the parameters to yield 1 μm particles, 5 μm particles, or any size in between—all with low polydispersity. This kit affords scientists the synthetic control and reproducibility needed to encapsulate drugs, proteins, or other molecules with polymer microparticles of a chosen size and drug loading. With this kit, researchers can quickly identify the ideal microparticle size and drug loading for their research application. PLGA is a biocompatible and biodegradable polymer that has been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.

특징 및 장점

  • Flexible synthesis tool to create uniform and reproducible nanoparticles
  • Optimized to make microparticles 1-5 μm by microfluidics with low polydispersity
  • Enables microparticle formulation screening and optimization of microparticles 1-5 μm to select ideal particle size for enhanced drug loading and controlled release
  • Based on non-toxic, biodegradable polymers

법적 정보

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

12 - Non Combustible Liquids


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문서 라이브러리 방문

문서

NanoFabTx™ platform accelerates drug development with ready-to-use formulations and microfluidic devices for particle synthesis.

NanoFabTX kits enable precise drug delivery with lipid nanoparticles and liposomes for mRNA and nucleic acids.

Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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