추천 제품
product name
trans-4-Hydroxy-L-proline, ≥99%
Quality Level
분석
≥99%
형태
crystalline powder
광학 활성
[α]25/D −75.6°, c = 1 in H2O
반응 적합성
reaction type: solution phase peptide synthesis
색상
white to off-white
mp
273 °C (dec.) (lit.)
응용 분야
peptide synthesis
SMILES string
O[C@H]1CN[C@@H](C1)C(O)=O
InChI
1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
InChI key
PMMYEEVYMWASQN-DMTCNVIQSA-N
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일반 설명
Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids.
애플리케이션
Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.
기타 정보
Natural constituent of animal structural proteins such as collagen and elastin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
Tetrahedron Letters, 35, 6163-6163 (1994)
Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli
BMC biotechnology, 14, 1-8 (2014)
Synthetic Communications, 23, 2691-2691 (1993)
Tetrahedron, 49, 6195-6195 (1993)
Tissue engineering. Part A, 25(11-12), 830-841 (2018-05-10)
Notochordal cells (NCs) reside in the core of the healthy disc and produce soluble factors that can stimulate nucleus pulposus cells (NPCs). These NC-derived factors may be applied in intervertebral disc regeneration for treatment of low-back pain. However, identification of
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