QBD11471

MAL-dPEG^®₁₂-Tris(m-dPEG^®₂₄)₃

>95% (HPLC)

• 동의어(들): Branched Maleimide-PEG-m, Branched mPEG-maleimide, MAL-NH-PEG₆₀₀-Tris(mPEG₁₀₀₀)₃, MAL-PEG₁₂-Tris(m-PEG₂₄)₃
• 실험식(Hill 표기법): C₁₉₄H₃₇₈N₆O₉₄
• Molecular Weight: 4299.06
• UNSPSC 코드: 12352106
• NACRES: NA.22

속성

• 분석: >95% (HPLC)
• 양식: solid or viscous liquid
• 반응 적합성: reaction type: Pegylations
• 폴리머 구조: functionality: monofunctional
• 배송 상태: ambient
• 저장 온도: −20°C

설명

특징 및 장점

MAL-dPEG₁₂-Tris(m-dPEG₂₄)₃ is a thiol-reactive, methyl-terminated, four-arm monodispersed PEG product designed to modulate biodistribution of conjugates. Tris forms the core of the molecule. Three equal-length methyl-terminated long arms plus one maleimido-terminated short arm extend from the tris core. From the maleimido olefin to the terminal methyl groups on each arm, the end-to-end length of this product is 127 atoms with an average distance of 103.7 Å. The amphiphilic PEG imparts hydrophilicity to conjugates, reduces or eliminates the conjugates′ antigenicity, and increases the hydrodynamic volume of conjugated molecules. Applications for this product include eradicating renal clearance, maintaining in vivo circulation for more extended periods, and suppressing immune responses to conjugates.

법적 정보

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable