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840861C

Avanti

18:0-18:1 PA

1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt), chloroform

동의어(들):

1-octadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); SOPA; PA(18:0/18:1(9Z))

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C39H74O8PNa
CAS Number:
384833-24-3
Molecular Weight:
724.96
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 2.5 mL (840861C-25mg)

제조업체/상표

Avanti Research™ - A Croda Brand 840861C

농도

10 mg/mL (840861C-25mg)

지질 유형

phospholipids

배송 상태

dry ice

저장 온도

−20°C

InChI

1S/C39H75O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,37H,3-17,19,21-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/b20-18-;/t37-;/m1./s1

InChI key

QTWIAVIWKTYOHY-HTNAYUJGSA-M

일반 설명

18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate) is an unsaturated phosphatidic acid (PA) derivative. PA is present in the biomembranes. It is the simplest glycerophospholipid.

애플리케이션

18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)) may be used:
  • as a phosphatidic acid (PA) standard to identify the corresponding radiolabeled PA on the thin-layer chromatography (TLC)
  • in vesicles for experimental validation in order to identify novel phospholipids capable of inhibiting cellular membrane transportation by (ATP)-binding cassette P-glycoprotein (P-gp)
  • to treat young adult mouse colonic (YAMC) cells prior to nanoclustering- forster resonance energy transfer (FRET) analysis(6)

생화학적/생리학적 작용

Phosphatidic acid (PA) is the precursor for other phospholipids and acts as a signaling molecule.

포장

5 mL Clear Glass Sealed Ampule (840861C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard
GHS06,GHS08

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

WGK

WGK 3

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Natividad R Fuentes et al.
Cancer research, 78(14), 3899-3912 (2018-05-18)
Ras signaling originates from transient nanoscale compartmentalized regions of the plasma membrane composed of specific proteins and lipids. The highly specific lipid composition of these nanodomains, termed nanoclusters, facilitates effector recruitment and therefore influences signal transduction. This suggests that Ras
Xavier Lucas et al.
PloS one, 8(4), e60679-e60679 (2013-04-18)
P-glycoprotein is capable of effluxing a broad range of cytosolic and membrane penetrating xenobiotic substrates, thus leading to multi-drug resistance and posing a threat for the therapeutic treatment of several diseases, including cancer and central nervous disorders. Herein, a virtual
Y Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 295(3), L471-L478 (2008-07-16)
We have previously reported the participation of mitogen-activated protein, Rho, and phosphoinositide-3 (PI3) kinases in separate pathways in serotonin (5-HT)-induced proliferation of pulmonary artery smooth muscle cells (SMCs). In this study, we investigated the possible participation of phospholipase D (PLD)
Jolanta Zegarlińska et al.
Acta biochimica Polonica, 65(2), 163-171 (2018-06-19)
Phosphatidic acid (PA) is the simplest glycerophospholipid naturally occurring in living organisms, and even though its content among other cellular lipids is minor, it is drawing more and more attention due to its multiple biological functions. PA is a precursor
Tingting Wang et al.
Frontiers in endocrinology, 9, 221-221 (2018-05-22)
Searching for nutraceuticals and understanding the underlying mechanism that promote fish growth is at high demand for aquaculture industry. In this study, the modulatory effects of soy phosphatidic acids (PA) on cell proliferation, nutrient sensing, and metabolic pathways were systematically

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