추천 제품
설명
n-dodecylphosphocholine
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 1 g (850336P-1g)
pkg of 1 × 25 g (850336P-25g)
pkg of 1 × 5 g (850336P-5g)
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
InChI
1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3
InChI key
QBHFVMDLPTZDOI-UHFFFAOYSA-N
일반 설명
Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification.Dodecylphosphocholine has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery.
MAPCHO™-12 or n-dodecylphosphocholine is a detergent with short chain.
애플리케이션
MAPCHO™-12 is suitable for use as detergent for B. subtilis cytochrome b558 protein for nuclear magnetic resonance experiments. It is also suitable for use in the purification of cytoplasmic tail of gp41 (gp41CT) protein and micelle preparation.
생화학적/생리학적 작용
MAPCHO™-12 or n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins. It provides a zwitterionic surface in the membrane micelle structure.
포장
125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-5g)
20 mL Clear Glass Screw Cap Vial (850336P-1g)
250 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-25g)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Magnetically oriented dodecylphosphocholine bicelles for solid-state NMR structure analysis
Nolandt OV, et al.
Biochimica et Biophysica Acta - Biomembranes, 1818(5), 1142-1147 (2012)
Solution structure and membrane interaction of the cytoplasmic tail of HIV-1 gp41 protein
Murphy RE, et al.
Structure, 25(11), 1708-1718 (2017)
Nina Liu et al.
Heliyon, 5(12), e03018-e03018 (2020-01-01)
Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined "class I″ viral glycoproteins, the formation of a highly stable α-helical bundle by the ectodomain of the fusion subunit (e.g., GP2 for
N P Santisteban et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183199-183199 (2020-01-29)
The lipid bilayer disrupting effect of antimicrobial peptides (AMPs) has been widely studied in model-lipid systems by applying biophysical techniques such as 2H NMR spectroscopy. Real bacteria cell envelopes contain non-lipid components, such as peptidoglycan, and thus it is important
Sheeja V Vasudevan et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(15), 6847-6851 (2010-03-31)
Repair of damage to the central nervous system (CNS) is inhibited by the presence of myelin proteins that prevent axonal regrowth. Consequently, growth inhibitors and their common receptor have been identified as targets in the treatment of injury to the
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