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Merck
모든 사진(2)

주요 문서

850399C

Avanti

24:1 (Cis) PC

1,2-dinervonoyl-sn-glycero-3-phosphocholine, chloroform

동의어(들):

1,2-di-(15Z-tetracosenoyl)-sn-glycero-3-phosphocholine; PC(24:1(15Z)/24:1(15Z)); 110930

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About This Item

실험식(Hill 표기법):
C56H108NO8P
CAS Number:
Molecular Weight:
954.43
MDL number:
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

양식

liquid

포장

pkg of 1 × 2.5 mL (850399C-25mg)

제조업체/상표

Avanti Research - A Croda Brand 850399C

농도

10 mg/mL (850399C-25mg)

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1

InChI key

REWNAIYQZZOESC-CGKZWXATSA-N

일반 설명

Phosphatidylcholine (PC) is a zwitterionic glycerophospholipid. PC constitutes the major phospholipid in the eukaryotic membrane. Among bacteria, only 10% has PC in their membrane.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

애플리케이션

24:1 (Cis) PC is suitable for use as a phospholipid (PL) standard for lipid profiling of phosphatidylcholine by electrospray ionization mass spectrometry (ESI-MS/MS).
24:1 (Cis) PC has been used:
  • in the preparation of multivesicular liposomes (DepoFoam) formulation with protein or peptide drugs
  • in the formation of planar bilayer lipid membranes
  • for analyzing the phase transition of giant unilamellar dinervonoylphosphocholine (DNPC) vesicles by N-4-nitrobenz-2-oxa-1,3-diazol (NBD)-labelled fluorophore in confocal microscopy

생화학적/생리학적 작용

24:1 (Cis) PC is a synthetic lipid.
Phosphatidylcholine (PC) is essential for the structure and functions of eukaryotic membranes. PC is essential for very low-density lipoprotein synthesis in liver cells. PC is the substrate for sphingomyelin. PC is the major source of cell signaling molecules. PC is the structural component of many human parasites and helps in cell invasion.

포장

5 mL Clear Glass Sealed Ampule (850399C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

WGK

WGK 3


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시험 성적서(COA)

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문서 라이브러리 방문

[TM="DepoFoam"] technology: a vehicle for controlled delivery of protein and peptide drugs
Ye Q, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 64(1-3), 155-166 (2000)
Observation of the main phase transition of dinervonoylphosphocholine giant liposomes by fluorescence microscopy
Metso AJ, et al.
Biochimica et Biophysica Acta - Biomembranes, 1713(2), 83-91 (2005)
Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore
Sobko AA, et al.
The Journal of Biological Chemistry, 281(20), 14408-14416 (2006)
Extraction and profiling of plant polar glycerol lipids
Liu Yu and Wang X
Bio-protocol (2016)
Activating and deactivating roles of lipid bilayers on the Ca2+-ATPase/phospholamban complex
Gustavsson M, et al.
Biochemistry, 50(47), 10367-10374 (2011)

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