추천 제품
분석
>99% (TLC)
형태
liquid
포장
pkg of 1 × 2.5 mL (850398C-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand 850398C
농도
10 mg/mL (850398C-25mg)
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
InChI
1S/C52H100NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,50H,6-19,24-49H2,1-5H3/b22-20+,23-21+/t50-/m1/s1
InChI key
SDEURMLKLAEUAY-QVOKQPLLSA-N
일반 설명
22:1 (Cis) PC (1,2-dierucoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It has two 22 carbon fatty acid chains, each having one cis double bond at the 13th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
애플리케이션
22:1 (Cis) PC (1,2-dierucoyl-sn-glycero-3-phosphocholine) has been used in liposome preparation and as a standard in the optimization of the LC−MS method conditions. It may be used to prepare planar bilayer lipid membranes (BLMs) to study its effects on the dependence of single-channel properties of C-terminal colicin peptide (P178). It may also be used in vesicles/bilayers to reconstitute the labeled protein mutant/for the reconstitution of coat protein.
생화학적/생리학적 작용
Phosphatidylcholine (PC) is capable of forming a strong bilayer.
포장
5 mL Clear Glass Sealed Ampule (850398C-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
신호어
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
표적 기관
Central nervous system, Liver,Kidney
WGK
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Dependence of M13 major coat protein oligomerization and lateral segregation on bilayer composition.
Fábio Fernandes et al.
Biophysical journal, 85(4), 2430-2441 (2003-09-26)
M13 major coat protein was derivatized with BODIPY (n-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-yl)methyl iodoacetamide), and its aggregation was studied in 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and DOPC/1,2-dioleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] (DOPG) or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE)/DOPG (model systems of membranes with hydrophobic thickness matching that of the protein) using photophysical methodologies (time-resolved
Gareth R Tibbs et al.
The Journal of pharmacology and experimental therapeutics, 345(3), 363-373 (2013-04-04)
Chronic pain after peripheral nerve injury is associated with afferent hyperexcitability and upregulation of hyperpolarization-activated, cyclic nucleotide-regulated (HCN)-mediated IH pacemaker currents in sensory neurons. HCN channels thus constitute an attractive target for treating chronic pain. HCN channels are ubiquitously expressed;
Alexander G Karabadzhak et al.
Biophysical journal, 114(9), 2107-2115 (2018-05-10)
The physical properties of lipid bilayers, such as curvature and fluidity, can affect the interactions of polypeptides with membranes, influencing biological events. Additionally, given the growing interest in peptide-based therapeutics, understanding the influence of membrane properties on membrane-associated peptides has
Alexander A Sobko et al.
The Journal of biological chemistry, 281(20), 14408-14416 (2006-03-25)
Colicin E1 belongs to a group of bacteriocins whose cytotoxicity toward Escherichia coli is exerted through formation of ion channels that depolarize the cytoplasmic membrane. The lipid dependence of colicin single-channel conductance demonstrated intimate involvement of lipid in the structure
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