850522P

Facade^™-EM

3α-hydroxy-7α,12α-di-((O-β-D-maltosyl)-2-hydroxyethoxy)-cholane, powder

• 동의어(들): FA-3; 3α-hydroxy-7α,12α-di-((O-Β-D-maltopyranosyl)ethyloxy)-cholane
• 실험식(Hill 표기법): C₅₂H₉₀O₂₅
• CAS Number: 1429405-95-7
• Molecular Weight: 1115.26
• UNSPSC 코드: 12161902
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 형태: powder
• 분자량: 1115.26 g/mol
• 포장: pkg of 1 × 1 g (850522P-1g); pkg of 1 × 200 mg (850522P-200mg); pkg of 1 × 25 mg (850522P-25mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 850522P
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCO[C@@H]4[C@@H](O)[C@H](O)[C@@H](O[C@H]5[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O5)[C@H](CO)O4)([H])C[C@H](OCCO[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)[C@@H](CO)O6)[C@@]

설명

일반 설명

Facade-EM is a two-dimensional amphiphile with hydrophobic and hydrophilic faces that has superior ability to stabilize integral membrane proteins. This new class of detergents represents a departure from traditional one-dimensional polar-head/nonpolar-tail molecules.

애플리케이션

Facade^™EM (3α-hydroxy-7α,12α-di-((O-β-D-maltosyl)-2-hydroxyethoxy)-cholane) may be used:

• as a facial amphiphile detergent to purify protoxin-II (ProTx2)-voltage-sensor domain II (VSD2)-voltage-gated sodium (NavAb) channel
• as an additive in fluorescence quenching experiments of pentaene-SM 18
• to form isotropic bicelles with p75 for nuclear magnetic resonance (NMR) studies

생화학적/생리학적 작용

Facades can be used for the crystallization of membrane proteins since they are considered as optimized membrane mimetics.

포장

20 mL Clear Glass Screw Cap Vial (850522P-1g)

20 mL Clear Glass Screw Cap Vial (850522P-200mg)

5 mL Amber Glass Screw Cap Vial (850522P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Facade is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids