추천 제품
분석
>99% (TLC)
형태
powder
분자량
796.95 g/mol
포장
pkg of 1 × 25 mg (850539P-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand 850539P
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCOP(OCC[N+](C)(C)C)([O-])=O)([H])C[C@H](OCCOP(OCC[N+](C)(C)C)([O-])=O)[C@@]4(C)[C@@]1([H])CC[C@@H]4[C@H](C)CCC
애플리케이션
Facade™-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.
생화학적/생리학적 작용
Facade™ EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.
Facade™ is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.
포장
5 mL Amber Glass Screw Cap Vial (850539P-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Facade is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Faccade detergents as bicelle rim-forming agents for solution NMR spectroscopy
Nanotechnology Reviews, 6(1), 93-103 (2017)
Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding xenobiotic metabolism
Molecular Pharmacology, 89(4), 435-445 (2016)
Phase Transitions in Small Isotropic Bicelles
Langmuir, 34(11), 3426-3437 (2018)
Proceedings of the National Academy of Sciences of the United States of America, 110(13), E1203-E1211 (2013-03-13)
Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and
Designing facial amphiphiles for the stabilization of integral membrane proteins.
Angewandte Chemie (International ed. in English), 46(37), 7023-7025 (2007-08-11)
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